The most effective way to lower cholesterol or low density
lipoproteins (LDL-C) is to take a statin – a medicine that works by
blocking an enzyme that causes the liver to produce cholesterol. LDL-C
is used as the best measure of blood fat (lipid level).
Medical experts recommend statin cholesterol lowering therapy for all
people with proven coronary heart disease (CHD), especially those who
have had a bypass or angioplasty. Many people with diabetes are high
risk and will benefit from being on a statin.

Statin cholesterol lowering therapy is also used regularly for
familial hypercholesterolaemia.
Cholesterol targets are defined in the New Zealand Cardiovascular
Guidelines. It is important to reach these lower targets to reduce the
risk of heart attacks and stroke.